2004-2008 华中农业大学 bwin必赢 应用生物技术专业 理学学士学位

2007-2012 华中农业大学 bwin必赢 微生物学专业 理学博士学位

科研与学术工作经历

2013-至今 bwin必赢 讲师

研究方向

抗结核小分子化合物的抑菌机制研究

代表性研究成果

论文

1. Feng Huang and Zheng-Guo He* (2010) Characterization of an interplay between a Mycobacterium tuberculosis MazF homolog, Rv1495 and its sole DNA topoisomerase I. Nucleic Acids Res., 38(22):8219-8230.

2. Feng Huang and Zheng-Guo He*（2012）Characterization of a Conserved Interaction between DNA Glycosylase and ParA in Mycobacterium smegmatis and M. tuberculosis. PLoS ONE, 7(6):e38276.

3. Qiong Yang, Feng Huang, Lihua Hu, Zheng-Guo He*(2012). Physical and functional interactions between 3-methyladenine DNA glycosylase and topoisomerase I in mycobacteria. Biochemistry (Mosc). 77(4):378-87.

4. Qiong Yang, Yuanyuan Liu, Feng Huang, Zheng-Guo He* (2011) Physical and functional interaction between D-ribokinase and topoisomerase I has opposite effects on their respective activity in M. smegmatis and M. tuberculosis Arch. Biochem. Biophys. 512(2):135-142.

5. Hua Zhang, Yuxi Tian, Ziduo Liu, Feng Huang, Lihua Hu, Zheng-Guo He* (2011) Characterization of amino acid residues essential for tetramer formation and DNA-binding activity of the ssDNA-binding protein of Mycobacterium tuberculosis. Biochemistry (Mosc). 76(6):658-665.

6. Yanli Du, Hua Zhang, Yang He, Feng Huang and Zheng-Guo He*（2012）. Mycobacterium smegmatis Lsr2 physically and functionally interacts with a new flavoprotein involved in bacterial resistance to oxidative stress. J Biochem. 152(5):479-486.

7. Yi Wang, Tao Cui, Cong Zhang, Min Yang, Yuanxia Huang, Weihui Li, Lei Zhang, Chunhui Gao, Yang He, Yuqing Li, Feng Huang, Jumei Zeng, Cheng Huang, Qiong Yang, Yuxi Tian, Chunchao Zhao, Huanchun Chen, Hua Zhang, Zheng-Guo He* (2010) Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv. J Proteome Res. 9（12）：6665 - 6677.